Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2

Myeloid ecotropic insertion site (Meis)2 is a homeodomain protein contain-ing a conserved homothorax (Hth) domain that is present in all Meis and Prep family proteins and in theDrosophilaHth protein. The Hth domain mediates interaction with Pbx homeodomain proteins, allowing for efficient DNA binding.