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báo cáo khoa hoc : Overexpression of Dsk2 ⁄dUbqln results in severe developmental defects and lethality in Drosophila melanogaster that can be rescued by overexpression of the p54 ⁄Rpn10 ⁄S5a proteasomal subunit

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

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Polyubiquitin receptors execute the targeting of polyubiquitylated proteins to the 26S proteasome. In vitro studies indicate that disturbance of the physiological balance among different receptor proteins impairs the prote-asomal degradation of polyubiquitylated proteins.

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Nội dung Text: báo cáo khoa hoc : Overexpression of Dsk2 ⁄dUbqln results in severe developmental defects and lethality in Drosophila melanogaster that can be rescued by overexpression of the p54 ⁄Rpn10 ⁄S5a proteasomal subunit

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