Chapter 050. Hirsutism and Virilization (Part 4)
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PCOS is the most common cause of ovarian androgen excess (Chap. 341). However, the increased ratio of LH to follicle-stimulating hormone that is characteristic of carefully studied patients with PCOS is not seen in up to half of these women due to the pulsatility of gonadotropins. If performed, ultrasound shows enlarged ovaries and increased stroma in many women with PCOS. However, polycystic ovaries may also be found in women without clinical or laboratory features of PCOS. Therefore, polycystic ovaries are a relatively insensitive and nonspecific finding for the diagnosis of ovarian hyperandrogenism. Although not usually necessary, gonadotropin-releasing hormone agonist...
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