Mass Spectrometry 2

If you read March’s paper on ion traps: – What is resonant excitation? Summarize how resonant excitation is used in typical ion trap MS experiments. If you read the Russell and Edmondson paper on MALDITOF and accurate mass: – Summarize the advantages and disadvantages of MALDI-TOF (with DE and reflection) versus FTICR (including ESI-FTICR), especially in biochemical applications. If you read the Aeberold and Goodlett proteomics paper: – Why is MS used so heavily in the study of post-translational modifications? Briefly describe an application to phosphopeptide sequence determinations....