So sánh breast stimulation test và oxytocin challenge test trong đánh giá sức khỏe thai

Y Hoïc TP. Hoà Chí Minh * Taäp 11 * Phuï baûn Soá 1* 2007<br /> <br /> Nghieân cöùu Y hoïc<br /> <br /> SO SAÙNH BREAST STIMULATION TEST VAØ OXYTOCIN CHALLENGE TEST<br /> TRONG ÑAÙNH GIAÙ SÖÙC KHOÛE THAI<br /> Voõ Thò Thuøy Dieäu*, Nguyeãn Duy Taøi**<br /> <br /> TOÙM TAÉT<br /> Stress Test (ST) laø moät chöùng nghieäm coù yù nghóa trong vieäc löôïng giaù khaû naêng chòu ñöïng cuûa thai qua<br /> moät cuoäc chuyeån daï sanh ngaõ aâm ñaïo. Phöông phaùp se ñaàu vuù luaân phieân caùch quaõng coù khaû naêng taïo côn<br /> co töû cung ñeå ñaùnh giaù thöû nghieäm gioáng nhö vieäc söû duïng Oxytocin ngoaïi sinh.<br /> Muïc tieâu: So saùnh phöông phaùp se ñaàu vuù vôùi söû duïng Oxytocin ngoaïi sinh trong vieäc taïo côn co töû<br /> cung ñeå thöïc hieän Stress Test.<br /> Phöông phaùp nghieân cöùu: Thieát keá nghieân cöùu thöû nghieäm laâm saøng ngaãu nhieân coù ñoái chöùng, vôùi 200<br /> saûn phuï taïi Beänh vieän Huøng Vöông, 100 saûn phuï ñöôïc tieán haønh laøm OCT vaø 100 saûn phuï ñöôïc tieán haønh<br /> laøm BST.<br /> Keát quaû: Khaû naêng taïo côn co chuaån cuûa caû 2 phöông phaùp OCT vaø BST khaù cao vaø töông ñoàng nhau,<br /> laàn löôït laø 93% vaø 89% (p = 0,687). Phöông phaùp se ñaàu vuù coù khaû naêng giaûm thieåu ñöôïc thôøi gian tieán<br /> haønh laøm nghieäm phaùp 20 phuùt so vôùi phöông phaùp OCT kinh ñieån tröôùc ñaây: BST: 9,08 ± 6,87 phuùt; OCT:<br /> 28,09 ± 16,23 phuùt (p < 0,001). Hoäi chöùng côn co cöôøng tính trong nhoùm OCT: 3%, trong nhoùm BST: 5%<br /> (p = 0,470).<br /> Keát luaän: BST coù theå thay theá OCT nhaèm tieát kieäm thôøi gian thöû nghieäm.<br /> Töø khoùa: Stress Test (ST), Breast Stimulation Test (BST), Oxytocin Challenge Test (OCT), Nipple<br /> Stimulation<br /> <br /> ABSTRACT<br /> COMPARISON OF BREAST STIMULATION TEST AND OXYTOCIN CHALLENGE TEST FOR<br /> ASSESSMENT OF FETAL WELL-BEING<br /> Vo Thi Thuy Dieu, Nguyen Duy Tai<br /> * Y Hoc TP. Ho Chi Minh * Vol. 11 – Supplement of No 1 – 2007: 214 - 220<br /> Background: Stress Test (ST) was found to be one of the reliable tests for assessment of fetal wellbeing. Intermittent breast stimulation has ability to induce uterine contraction to evaluate test as Oxytocin<br /> Challeng Test.<br /> Objective: To compare nipple stimulation and exogenous oxytocin in inducing uterine contractions for<br /> Stress Test.<br /> Methods: A prospective randomized controlled trial conducted at Hung Vuong hospital, 200 pregnant<br /> women who had indication for Stress test were enrolled in the study: one hundred in BST group and one<br /> hundred in OCT group. These data were analyzed with analysis of variance, Chi-square test, t-test.<br /> Results: Effective uterine contractions were found in 93% of the OCT group and 89% of the BST<br /> group (p = 0.687). Mean duration for achievement of a contraction stress test was found to be<br /> significantly different between two group (9.08 ± 6.87 minutes vs 28.09 ± 16.23 minutes in the BST group<br /> and OCT group, respectively – p