Allele frequency

Research objective: Establish the genetic variants database of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Identification of genotype and allele frequencies of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Perform in silico functional analysis of novel variants.

27p extraenglish 24-05-2021 23 4   Download

Establish the genetic variants database of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Identification of genotype and allele frequencies of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Perform in silico functional analysis of novel variants.

27p capheviahe27 23-02-2021 4 3   Download

To describe EEG and relationship between EEG and clinical features in patients with schizophrenia. To assess the frequency of allele and genotypic distribution of ZNF804A gene polymorphism rs1344706 and COMT gene polymorphism rs165599 in patients with schizophrenia.

37p cothumenhmong6 17-07-2020 20 2   Download

Determining the frequency of genotype and allele of TNF-α – 308 and TGF-β1-509 in HCC patients with HBsAg (+). Analysing the association of TNF-α-308, TGF-β1-509 polymorphism with risk of HCC and some clinical and subclinical characteristics of HCC patients.

28p cothumenhmong6 17-07-2020 12 0   Download

To assess the frequency allele and genotypic distribution of polymorphism rs165599 in catechol-O-methyltransferase in Kinh ethnic-patients with schizophrenia. Subjects and methods: A case-control study consisted of 227 schizophrenic patients and 92 healthy controls in the Kinh ethnic. The rs165599 was genotyped by PCR-RFLP and statistical analysis was performed by Chi-Square test. Results: The frequency of allele A and G in schizophrenic patients were 72.36% and 69.94%, respectively. The frequency of allele A and G in healthy controls were 27.64% and 30.06%, respectively (p > 0.05).

6p chauchaungayxua1 02-12-2019 25 1   Download

In the majority of hypophosphatasia patients, reductions in the serum lev-els of alkaline phosphatase activity are caused by various missense muta-tions in the tissue-nonspecific alkaline phosphatase (TNSALP) gene. A unique frame-shift mutation due to a deletion of T at cDNA number 1559 [TNSALP (1559delT)] has been reported only in Japanese patients with high allele frequency.

14p awards 06-04-2013 38 3   Download

Two allelic isoforms (H1.a1 and H1.a2) of histone H1.a were identified within two conservative flocks (R11 and R55) of Rhode Island Red chick-ens. These proteins form three phenotypes: a1, a2 and a1a2. Birds with phenotype a1 were most common (frequency 0.825–0.980) while the a1a2 chickens appeared relatively rarely (0.017–0.175).

11p inspiron33 26-03-2013 52 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An attempt to modify allelic frequencies at the Adh locus of a Drosophila melanogaster population in a tropical environment

6p toshiba21 16-11-2011 36 3   Download

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Latitudinal clines of allelic frequencies in Mediterranean populations of Ceratitis capitata (Wiedemann)

0p toshiba20 15-11-2011 51 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients...

7p thulanh13 14-10-2011 38 1   Download

Population Genetics In population genetics, the focus changes from alterations in an individual's genome to the distribution pattern of different genotypes in the population. In a case where there are only two alleles, A and a, the frequency of the genotypes will be p2 + 2pq + q2 = 1, with p2 corresponding to the frequency of AA, 2pq to the frequency of Aa, and q2 to aa. When the frequency of an allele is known, the frequency of the genotype can be calculated. Alternatively, one can determine an allele frequency, if the genotype frequency has been determined. Allele frequencies vary...

5p konheokonmummim 03-12-2010 71 3   Download

Allelic Association, Linkage Disequilibrium, and Haplotypes Allelic association refers to a situation in which the frequency of an allele is significantly increased or decreased in individuals affected by a particular disease in comparison to controls. Linkage and association differ in several aspects. Genetic linkage is demonstrable in families or sibships. Association studies, on the other hand, compare a population of affected individuals with a control population.

5p konheokonmummim 03-12-2010 67 2   Download