Biology/ life science

Department of Biochemistry, Eotvos Lorand University, and 2Biotechnology Research Group of the Hungarian Academy of Sciences, ´ ´ ´ ´ Pazmany setany 1/C, Budapest, Hungary The molecular mechanism of the autolysis of rat a-chymotrypsin B was investigated. In addition to the two already known autolytic sites, Tyr146 and Asn147, a new site formed by Phe114 was identified. The former two sites and the latter one are located in the autolysis and the interdomain loops, respectivel

9p system191 01-06-2013 33 3   Download

Department of Medical Chemistry, Kochi Medical School, Nankoku, Japan; 2Department of Biochemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Japan; 3Department of Anatomy and Cell Biology, Kochi Medical School, Nankoku, Japan We previously generated mice lacking aromatase activity by targeted disruption of Cyp19 (ArKO mice), and reported phenotypes of the female mice, showing hemorrhage formation and follicular depletion in the ovary, diminution in uterine size, and bone loss...

9p research12 01-06-2013 40 4   Download

The 2006 Global BioMillennium Conference took place in Tbilisi, Georgia, on 13–17 July 2006. The Conference was focused on key aspects of gene expression processes. Characteristic of state-of-the-art research in the life sciences, the invited lectures spanned approaches in cell biology, gene expression, and protein function.

4p galaxyss3 21-03-2013 48 3   Download

Experimental design has a long tradition in statistics, engineering and life sciences, dating back to the beginning of the last century when optimal designs for industrial and agricultural trials were considered. In cell biol-ogy, the use of mathematical modeling approaches raises new demands on experimental planning.

17p vinaphone15 27-02-2013 40 3   Download

Control of transferrin expression by b-amyloid through the CP2 transcription factor Sang-Min Jang1,*, Jung-Woong Kim1,*, Chul-Hong Kim1, Joo-Hee An1, Eun-Jin Kang1, Chul Geun Kim2, Hyun-Jung Kim3 and Kyung-Hee Choi1 1 Department of Life Science (BK21 Program), College of Natural Sciences, Chung-Ang University, Seoul, Korea 2 Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul, Korea 3 College of Pharmacy, Chung-Ang University, Seoul, Korea Keywords Alzheimer’s disease; CP2; iron homeostasis; oxidative stress; transferrin Correspondence K.-H.

12p viettel02 19-02-2013 32 3   Download

Masaki Okumura1,2, Masatoshi Saiki2,3, Hiroshi Yamaguchi1 and Yuji Hidaka2 1 School of Science and Technology, Kwansei Gakuin University, Hyogo, Japan 2 Graduate School of Science and Engineering, Kinki University, Osaka, Japan 3 Department of Applied Chemistry, Faculty of Engineering, Tokyo University of Science, Yamaguchi, Japan Keywords arginine; disulfide; folding; glutathione; uroguanylin Correspondence Y.

8p cosis54 05-01-2013 43 4   Download

Department of Genome Sciences, Life Sciences Division, Lawrence Berkeley National Laboratory, One Cyclotron Rd, Berkeley, CA 94720, USA. †Department of Biology, University of Pennsylvania, 324 Leidy Laboratories, Philadelphia, PA 19104, USA. ‡Center for Integrative Genomics, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA. §Current address: Department of Genetics, Washington University, 4566 Scott Ave, St. Louis, MO 63110, USA. Correspondence: Justin C Fay. E-mail: jfay@genetics.wustl.

0p thulanh21 15-11-2011 58 2   Download

Opinion Predicting and validating microRNA targets Eric C Lai Address: 545 Life Sciences Addition, Department of Molecular and Cell Biology and Howard Hughes Medical Institute, University of California at Berkeley, Berkeley, CA 94720-3200, USA. E-mail: lai@fruitfly.org comment Published: 31 August 2004 Genome Biology 2004, 5:115 The electronic version of this article is the complete one and can be found online at http://genomebiology.

6p thulanh19 09-11-2011 38 2   Download

Physics has an important role in our life. Without physics and the work of physicists, our modern life would not exist. Using physics, people created machines, instruments and some different divices from the crudest to the most modern aspect. Techology is developed more rapidly, more modern day by day. Moreover, all other natural sciences- example chemistry, biology, medicinedepend upon physics for the foundations of their knowledge.

17p tieulaubau 21-06-2011 84 4   Download

năng lượng. favors. thiện ý, chiếu cố. engineering. kỹ thuật. feather. lông vũ ... thuyết hưu cơ. natural process. tiến trình tự nhiên.neuron : tế bào thần kinh, neuron; nitrogen base: chất kiểm có nhóm nitrogen; osmosis * sự thẩm lọc; parent: Cha mẹ, nguồn gốc; particle: phần tử; path way: đường nhỏ, đường mòn; rare: hiếm; reaction; phản ứng; reagent: chất phản ứng, thuốc thử; random: một cách bất kỳ....

12p ngoclanh 10-06-2009 317 125   Download