Cancer cell

To evаluаte 18FDG PET-CT for the prediction of overаll survivаl in pаtients with smаll cell lung cаncer аfter concurrent chemoradiotherapy. Methods: Forty pаtients with pаthologicаlly proven stаge III аnd III SCLC hаd FDG PET-CT scаns before concurrent chemorаdiotherаpy. The mаximum stаndаrdized uptаke vаlue (SUVmаx) of the primаry lung lesion wаs cаlculаted.

6p vihizuzen 26-05-2025 2 1   Download

To evaluate the diagnostic value of PTGER4 (Prostaglandin E Receptor 4) gene methylation in plasma for lung cancer detection compared to healthy controls. Methods: A cross-sectional, case-control study was conducted on 149 non-small cell lung cancer (NSCLC) patients and 100 healthy individuals. Peripheral blood samples were collected for PTGER4 methylation analysis using real-time methylation-specific PCR (MSP).

8p vimitsuki 06-05-2025 1 1   Download

To establish a protocol for analyzing NK cell cytotoxic activity (NKAc) in breast cancer patients using the flow cytometric technique. Methods: We first optimized the protocol based on the previously published studies, focusing on choosing fluorescent dye concentration, incubation time length, and Effector:Target cell ratio (E:T ratio). Subsequently, we preliminarily applied the established protocol to characterize NKAc in some breast cancer patients and healthy controls.

9p vimitsuki 06-05-2025 3 1   Download

Carcinoma in patients with traumatic brain injury having retained metal foreign bodies does not commonly exist. Complications of local cancer by traumatic brain injury, having retained metal foreign bodies can occasionally occur. Changes mainly appear at the wound due to chronic inflammation and cell hyperplasia, which leads to cancer.

5p vimitsuki 06-05-2025 1 1   Download

A novel series of s-triazine derivatives was designed and screened for in silico an cancer activity in histone deacetylase 6 (HDAC6) target by molecular docking method using AutoDock Vina.

10p vifilm 11-10-2024 3 1   Download

A fragment-based approach has been applied to derive 2-(7-hydroxy-2-oxo-2H-chromen-4- yl)acetic acid 1 into 4 new coumarin derivatives 2a-d through amide bonds. The compounds were screened for their anticancer activity using MTT assay on MCF-7 and HepG2 cell lines.

10p viaburame 14-03-2025 4 0   Download

Garlic has been utilized since ancient times for both culinary and medicinal purposes. Recent research has identified selenium compounds in garlic, including γ-Glutamyl-Se-methylselenocysteine (GGMSC), leading to the hypothesis that GGMSC acts as a carrier for Se-methylselenocysteine (MSC). Experiments conducted on animals by researchers indicate that the effects of GGMSC in garlic and MSC on cancer cells in experimental models are equivalent. This finding suggests that garlic is a potential chemotherapeutic agent to enhance cancer treatment.

5p tuongmotranh 18-03-2025 3 1   Download

A benzothiazole ring plays an important role in pharmacological target diseases, including metabolic diseases, cancer, anti-inflammatory, neurodegeneration, viral diseases, bacterial infections, fibrosis, and thrombosis. Hydrazone-hydrazide derivatives are present in numerous biological molecules and play a significant role in medicine and pharmacology.

9p viaburame 14-03-2025 2 1   Download

Breast cancer is the most common malignancy and the second leading cause of death in women. While tamoxifen (TAM) remains to be a first-line agent for prevention and treatment of estrogenreceptor (ER) positive breast tumors, TAM resistance represents one of the biggest clinical challenges in breast cancer therapy.

9p vihyuga 04-03-2025 3 1   Download

This study aims to present a case of pneumonitis in a patient treated with concurrent chemoradiotherapy (cCRT) followed by durvalumab, focusing on the clinical manifestations, management strategies, and the implications for medical practice.

6p viyamanaka 06-02-2025 6 2   Download

Extended mediastinal with bilateral recurrent laryngeal nerves (RLNs) lymph node dissection (LND) is critical to curative surgery in the treatment of esophageal squamous cell carcinoma (ESCC). Some reports in Robotic transthoracic esophagectomy (RTE) have some advantages over Thoracoscopic esophagectomy (TE) in increasing the exposure and accuracy of mediastinal LND. However, published data was still limited.

9p viakimichi 17-01-2025 4 2   Download

Green tea consumption has been shown to exhibit cancer-preventive activities in preclinical studies. Polyphenon E (Poly E) is a green tea standardized extract. This study was undertaken to examine the antiproliferative effect and pro-oxidant activity of Poly E on PC3 prostate cancer cells.

5p viuchiha 06-01-2025 2 1   Download

Colorectal cancer (CRC) is one of the most common malignant cancers of the colon worldwide. Several novel approaches to cancer treatment have emerged, including gene therapy, targeted therapy, and adjuvant therapies.

7p viharuno 03-01-2025 6 2   Download

Studies on nanoparticle-protein interaction have also not been studied. This would give information on ratio influence on the structural alteration of EGCg in EGCg-AuNPs and its functionality in vivo. Herein, the optimisation of EGCg-AuNPs will be determined with a large pool of stoichiometric synthesises of gold and EGCg. These optimised EGCg-AuNPs would then be studied with bovine serum albumin (BSA) for protein interactions, binding and thermodynamics.

177p runthenight07 01-03-2023 12 3   Download

The objectives of the thesis: Determine the chemical composition of three soft coral species S. nanolobata, S. conferta, S. leptoclados collected in the central sea of Vietnam; đetecting active substances with cytotoxic activity in soft corals studied, orienting their application for biomedical and pharmacological studies.

26p closefriend09 16-11-2021 17 4   Download

The purpose of the thesis research: Synthesis of new complexes of platinum and rare-earth elements containing quinoline's derivatives that are resistant to cancer cells, high antimicrobial activity or good fluorescence.

27p tunelove 10-06-2021 24 4   Download

Objectives: Assessment of anti-human colon cancer cell (HT-29 cell) efficacy and activating apoptosis of MeV and MuV combination in vitro. Assessment of C cell tumor efficacy of MeV and MuV combination in nude mice xenograft models.

26p petsematary 02-06-2021 12 3   Download

Demonstrating the main chemical constituents of Anodendron paniculatum (Roxb.) A.DC. Structural determination of isolated compounds; evaluation of the cytotoxic activities of isolated compounds against human cancer cell lines.

25p nguathienthan12 23-05-2021 14 3   Download

The research objectives of the thesis: Isolate and determine the chemical structure of compounds from C. candicans and C. macrophylla species collected in Vietnam. Assessment of toxic activity on some cancer cell lines: liver (Hep-G2), lung (Lu-1) and breast (MCF-7) of isolated clean compounds. Researching the chemical composition of C. candicans and C. macrophylla essential oils

29p extraenglish 24-05-2021 21 4   Download

Objective: Study on synthesis of nano dendrimer PAMAM with anticancer drugs carboplatin (CAR) and oxaliplatin (OXA) to reduce the toxicity of the drug to normal cells and improve the effectiveness on cancer cell destruction by increasing solubility, increasing drug storage capacity, targeting drugs passively.

27p extraenglish 24-05-2021 24 4   Download