Chronic liver disease

Chronic liver disease has a high global burden and death toll. Early diagnosis is important to halt disease progression to cirrhosis, hepatocellular carcinoma, and eventually death. At present, there are many methods used for liver disease assessment, such as liver biopsy, elastography, serum biomarkers, and surrogate markers.

5p vihizuzen 26-05-2025 3 1   Download

Metabolic-Associated Fatty Liver Disease (MAFLD) is affecting approximately 24% of individuals and potentially leading to cirrhosis and hepatocellular carcinoma. This study aims to assess the prevalence of MAFLD in chronic obstructive pulmonary disease (COPD) patients and analyze their clinical characteristics.

8p vijiraiya 19-05-2025 1 1   Download

Hepatitis B infection remains a global health problem, with progression to acute-chronic hepatitis, severe liver failure, and death making hepatitis B one of the most serious infections worldwide. The disease is most widely transmitted from an infected mother to her baby, after exposure to infected blood or body fluids or unsafe sexual contact.

6p viharuno 03-01-2025 3 2   Download

Intravenous iron, used for the treatment of anemia in chronic renal failure andother diseases, represents a possible source of free iron in tissue cells, particularly in the liver. In this study we examined the effect of different sources of intravenous iron (IVI) on the labile iron pool (LIP) which represents the nonferritin-bound, redox-active iron that is implicated in oxidative stress and cell injury. Furthermore, we examined the role of the LIP for the synthesis of ferritin.

8p tumor12 20-04-2013 51 4   Download

Chronic hepatitis C virus (HCV) infection is a clinically important liver disease with limited therapeutic options in a significant proportion of patients. Therefore, novel efficient therapeutic agents are needed. Because the 5¢- and 3¢-untranslated regions (UTRs) of HCV are highly conserved and functionally important for HCV replication, they are attractive targets for RNA-cleaving ribozymes or small interfering RNAs (siRNAs).

13p dell39 27-03-2013 52 5   Download

Hepatitis C virus is a human pathogen responsible for liver diseases includ-ing acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. Its high prevalence, the absence of a prophylactic vaccine and the poor effi-ciency of current therapies are huge medical problems. Since the discovery of the hepatitis C virus, our knowledge of its biology has been largely punctuated by the development of original models of research.

14p media19 04-03-2013 35 3   Download

The mechanisms whereby hepatic fibrosis develops in chronic liver diseases remain incompletely defined. Here, we sought to examine whether micro-RNA (miRNA) became dysregulated in dimethylnitrosamine-induced hepatic fibrosis in rats. Our microarray analysis revealed that the miR-34 family was upregulated along with other miRNAs in liver fibrotic tissues. Six miRNAs, such as rno-miR-878, were downregulated.

11p cosis54 05-01-2013 47 5   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Renal dysfunction in chronic liver disease...

10p coxanh_6 30-10-2011 46 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A prospective assessment of the inter-laboratory variability of biochemical markers of fibrosis (FibroTest) and activity (ActiTest) in patients with chronic liver disease...

10p thulanh17 27-10-2011 60 5   Download

Int. J. Med. Sci. 2008, 5 327 International Journal of Medical Sciences Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Efficacy of Radiofrequency Ablation of Hepatocellular Carcinoma Associated with Chronic Liver Disease without Cirrhosis...

6p thulanh8 06-10-2011 52 5   Download

Mục tiêu nghiên cứu Đánh giá mối liên quan giữa nồng độ virus viêm gan B (HBV) trong quá khứ và tỷ lệ tử vong do ung thư tế bào gan (HCC: hepatocellular carcinoma) và bệnh gan mạn tính (CLD: chronic liver disease) trong thời gian 10 năm ở những cư dân trưởng thành có HBsAg (+) tại thành phố Haimen, Trung Quốc. Phương pháp nghiên cứu Nhóm nghiên cứu được tuyển chọn từ năm 1992 – 1993. Mười năm sau đó, chúng tôi kiểm tra mối liên quan giữa nồng độ virus tại thời điểm đưa vào nghiên...

10p buddy7 28-06-2011 126 8   Download

The Model for End-Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease. It was initially developed to predict death within three months of surgery in patients who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure, and was subsequently found to be useful in determining prognosis and prioritizing for receipt of a liver transplant. This score is now used by the United Network for Organ Sharing (UNOS) and Eurotransplant for prioritizing allocation of liver transplants instead of the older Child-Pugh score. ...

3p truongthiuyen1 08-06-2011 91 6   Download

Is there a cure for chronic hepatitis B? The good news is that there are promising new treatments for people living with chronic hepatitis B. Today, there are several approved drugs in the United States that can slow down liver damage caused by the virus. The new drugs can help slow the progression of liver disease in chronically infected people by slowing down the virus. If there is less hepatitis B virus being produced, then there is less damage being done to the liver. Sometimes these drugs can even get rid of the virus. With all of the new...

4p duagangdamsua 24-05-2011 64 4   Download