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Evidence of clinical validity

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  • Adaptive behavior assessment system–II technical report provides a comprehensive norm-referenced assessment of the adaptive skills of individuals ages birth to 89 years. The clinician can use the ABAS–II to diagnose and classify disabilities and disorders; identify an individual’s strengths and limitations; and to document and monitor the individual’s performance over time. The ABAS–II provides for the assessment of an individual by multiple respondents (e.g.

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  • Evidence-Based Medicine The "art of medicine" is traditionally defined as a practice combining medical knowledge (including scientific evidence), intuition, and judgment in the care of patients (Chap. 1). Evidence-based medicine (EBM) updates this construct by placing a much-greater emphasis on the processes by which the clinician gains knowledge of the most up-to-date and relevant clinical research. The key processes of EBM can be summarized in four steps: 1. Formulating the management question to be answered 2.

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  • Sources of Evidence: Clinical Trials and Registries The notion of learning from observation of patients is as old as medicine itself. Over the last 50 years, our understanding of how best to turn raw observation into useful evidence has evolved considerably. Case reports, personal anecdotal experience, and small single-center case series are now recognized as having severe limitations to validity and have no role in formulating modern standards of practice. The major tools used to develop reliable evidence consist of the randomized clinical trial and the large observational registry.

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