Gastrointestinal medicine

This study was carried out to provide scientific proof to justify the intended medicinal use of PDDT tablets with two main objectives: 1) Investigate the effects of PDDT on mice’ intestinal motility; 2) Evaluate the effects of PDDT on rabbits’ isolated intestinal segments.

7p viyamanaka 06-02-2025 5 2   Download

Helicobacter pylori is a bacterium associated with gastric diseases and disorders of the upper gastrointestinal tract. The gram-negative bacterium Helicobacter pylori is known as a persistent colonizer of the human stomach, and this bacteria is also involved in extra-intestinal diseases. In 1994, the International Agency for Research on Cancer, World Health Organization classified H. pylori as a class 1 carcinogen, the only bacterium given this classification.

11p vinara 11-01-2025 2 1   Download

Gastrointestinal cancers, including liver cancer, colorectal cancer, and stomach cancer, are the most common cancers in the world as well as in Vietnam, posing a leading threat to human health. The cost of treating these cancers is a major problem that burdens not only patients but also healthcare systems. The study aims to analyze treatment costs for the four most common types of gastrointestinal cancer nowadays.

9p viharuno 03-01-2025 4 2   Download

Colorectal polyps are a relatively common diseases in the group of lower gastrointestinal tract diseases. The prevalence of colorectal polyps ranges from 20 to 50%. Objectives: (1) To describe some clinical and endoscopic features of colorectal polyps; (2) To evaluate the histopathological characteristics and the relationship between histopathology and some clinical and endoscopic features of colorectal polyps.

7p viharuno 03-01-2025 5 2   Download

Study the clinical characteristics, endoscopy, histopathology, expression of proteins p53, Ki67, Her- 2/neu in colorectal cancer and colorectal polyps greater than or equal to 10 mm; study the relationship between the expression of proteins p53, Ki67 and Her- 2/neu with histopathological characteristics, lymph node metastasis in colorectal cancer and colorectal polyps greater than or equal to 10 mm.

27p change04 08-06-2016 58 5   Download

ADH1 and ADH4 are the major alcohol dehydrogenases (ADH) in ethanol and retinol oxidation. ADH activity and protein expression were investigated in rat gastrointestinal tissuehomogenates by enzymatic andWesternblot analyses. In addition, sections of adult rat gastrointestinal tract were examined byin situ hybridization and immunohistochem-istry.ADH1andADH4weredetectedalong thewhole tract, changing their localization and relative content as a function of the area studied.

11p fptmusic 16-04-2013 36 2   Download

The major 2S albumin allergen from Brazil nuts, Ber e 1, was subjected to gastrointestinal digestion using a physiologically relevantin vitro model sys-tem either before or after heating (100
C for 20 min). Whilst the albumin was cleaved into peptides, these were held together in a much larger struc-ture even when digested by using a simulated phase 1 (gastric) followed by a phase 2 (duodenal) digestion system. Neither prior heating of Ber e 1 nor the presence of the physiological surfactant phosphatidylcholine affected the pattern of proteolysis.

0p awards 05-04-2013 42 2   Download

Type IIa bacteriocins, which are isolated from lactic acid bacteria that are useful for food preservation, are potent antimicrobial peptides with considerable potential as therapeutic agents for gastrointestinal infections in mam-mals. They are ribosomally synthesized as precursors with an N-terminal leader, typically 18–24 amino acid residues in length, which is cleaved during export from the produ-cing cell.

9p dell39 03-04-2013 47 5   Download

Mucin, a major component of mucus, is a highly O-glycosylated, high-molecular-mass glycoprotein extensively involved in the physiology of gastrointestinal mucosa. To detect and characterize mucins derived from site-specific mucous cells, we developed a monoclonal antibody, designated PGM34, by immunizing a mouse with purified pig gastric mucin.

16p galaxyss3 21-03-2013 37 4   Download

Parkinson’s disease (PD) is a heterogeneous movement disorder character-ized by progressive degeneration of dopamine neurons in substantia nigra. We have previously presented genetic evidence for the possible involvement of alcohol and aldehyde dehydrogenases (ADH; ALDH) by identifying genetic variants in ADH1C and ADH4 that associate with PD.

12p galaxyss3 21-03-2013 37 4   Download

Ulcerative colitis (UC) is a gastrointestinal disorder characterized by an inflammatory process associated with mucosal damage. Many studies have shown that n-3 polyunsaturated fatty acids (PUFAs) possess anti-inflam-matory effects in inflammatory bowel disease.

10p media19 05-03-2013 39 5   Download

Okadaic acid (OA) and its analogs, the dinophysistoxins, are potent inhibi-tors of protein phosphatases 1 and 2A. This action is well known to cause diarrhea and gastrointestinal symptons when the toxins reach the digestive tract by ingestion of mollusks. A less well-known effect of these group of toxins is their effect in the cytoskeleton.

7p vinaphone15 28-02-2013 44 2   Download