Immunological changes

There is increasing evidence that the intestinal microbiota plays a crucial role in the maturation of the immune system and the prevention of diseases during childhood. Early-life short-course antibiotic use may affect the progression of subsequent disease conditions by changing both host microbiota and immunologic development.

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To describe demographic and clinical characteristics of psoriasis patients at the Department of Dermatology, Venerology, and Allergology of 108 Military Central Hospital between August 2015 and May 2018.

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Discoid lupus erythematosus. Violaceous, hyperpigmented, atrophic plaques, often with evidence of follicular plugging, which may result in scarring, are characteristic of discoid lupus erythematosus (also called chronic cutaneous lupus erythematosus). Scleroderma and Morphea The skin changes of scleroderma (Chap. 316) usually begin on the hands, feet, and face, with episodes of recurrent nonpitting edema.

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Treatment The key to treatment is patient education. Teach patient to avoid triggers, have them change their environment, change their medication. If these are not feasible, then medical therapy is the next course of action. Immunologic therapy ahs no benefit to non-allergic rhinitis and therefore it is important to distinguish the disease before considering immunotherapy. Nasal lavage has been shown to have minor decongestion benefits and improves mucocilliary function. Topical nasal steroids have been used widely for use with NAR.

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