Medical center

Complications are considered the critical contributors to lower health-related quality of life among diabetes patients. Objectives: This study aimed to estimate utility of diabetes patients anhealth-state utilities among these populd identify potential predictors of ations.

18p vihizuzen 26-05-2025 1 1   Download

To investigate the prevalence and associated factors of vertebral compression fracture (VCF) in older women with osteoporosis. Methods: A crosssectional study was conducted on 279 older women with osteoporosis at the Rheumatology and Neurosurgery Department and Rheumatology Clinic, University Medical Center, from August 2022 to May 2023.

9p vimitsuki 06-05-2025 0 0   Download

This study aimed to assess the anxiety levels and experiences of patients connected to continuous monitoring systems. Conducted between February and May 2024 at the Cardiovascular Center (HMUH), the cross-sectional study involved 108 patients who had been continuously monitored for at least 24 hours.

7p viyamanaka 06-02-2025 8 2   Download

The Credit-Module System (CMS) has been applied in various countries in order to increase students’ independence and all-round competence. Based on CMS, students can take courses of their choice, learn at their own pace, and take additional courses. Students are the center of this educational system. Thus, undergraduate students’ attitudes and practices towards this system are critical in determining their academic achievement and quality of education.

7p vinara 11-01-2025 2 1   Download

The objective of this study is to examine the features of carotid ultrasound, including carotid intima-media thickness (cIMT) and carotid plaques (CP), and to compare these characteristics between individuals with RA and control subjects.

7p viharuno 03-01-2025 6 2   Download

Departamento de Fisiologıa de la Nutricion, Instituto Nacional de Ciencias Medicas y Nutricion ‘Salvador Zubiran’, Mexico; ´ ´ ´ ´ ´ Departamento de Patologıa Experimental, Instituto Nacional de Ciencias Medicas y Nutricion ‘Salvador Zubiran’,Mexico; 3Department of Biochemistry, Wake Forest University Medical Center, Winston-Salem, North Carolina, USA Branched chain amino-acid aminotransferase (BCAT) activity is present in fetal liver but the developmental pattern of mitochondrial BCAT (BCATm) expression in rat liver has not been studied.

8p system191 01-06-2013 49 6   Download

The functional replacement of the primary ubiquinone (QA) in the photosynthetic reaction center (RC) from Rhodo-bacter sphaeroideswith synthetic vitamin K derivatives has provided a powerful tool to investigate the electron transfer mechanism. To investigate the binding mode of these qui-nones to theQAbinding sitewe have determined the binding free energy and charge recombination rate from QA ± to D + (kAD) of 29 different 1,4-naphthoquinone derivatives with systematically altered structures.

13p research12 01-06-2013 53 4   Download

The core complex ofRhodobacter sphaeroidesis formed by the association of the light-harvesting antenna 1 (LH1) and the reaction center (RC). The PufX protein is essential for photosynthetic growth; it is locatedwithin the core in a 1 : 1 stoichiometry with the RC. PufX is required for a fast ubiquinol exchange between the QBsite of the RC and the Qo site of the cytochromebc1complex.

9p research12 23-04-2013 36 3   Download

Pigment epithelium-derived factor (PEDF), a neurotrophic and antiangiogenic protein, is an extracellular component of the retinal interphotoreceptor matrix which has been shown to be secreted by human fetal retinal pigment epithelial cells. It belongs to the serpin superfamily and contains the typical exposed reactive center loop. The functionof this loop is still unknown.

10p tumor12 20-04-2013 33 4   Download

Previous work from this laboratory has shown that the spectral and functional properties of a prokaryotic xanthine dehydrogenase fromComamonas acidovoransshow some similarities to those of the well-characterized eukaryotic enzymes isolated from bovine milk and from chicken liver [Xiang, Q. & Edmondson, D.E. (1996) Biochemistry35, 5441–5450]. Therefore, this system was chosen to study the factors involved in the expression of functional recombinant enzyme in Escherichia colito provide insights into the assembly of the functional Mo-pyranopterin center....

11p fptmusic 12-04-2013 40 2   Download

Transmembrane proton translocation in the photosynthetic membranes of the purple bacteriumRhodobacter sphaero-ides is driven by light and performed by two transmem-brane complexes; the photosynthetic reaction center and the ubiquinol–cytochromecoxidoreductase complex, coupled by two mobile electron carriers; the cytochrome and the quinone. This paper focuses on the kinetics and thermo-dynamics of the interaction between the lipophylic electron carrier ubiquinone-10 and the photosynthetic enzyme reconstituted in liposomes. ...

11p fptmusic 12-04-2013 62 2   Download

This work reports on the direct electrochemistry of the Desulfovibrio gigasaldehyde oxidoreductase (DgAOR), a molybdenum enzyme of the xanthine oxidase family that contains three redox-active cofactors: two [2Fe-2S] centers and a molybdopterin cytosine dinucleotide cofactor. The voltammetric behavior of the enzyme was analyzed at gold and carbon (pyrolytic graphite and glassy carbon) elec-trodes. Two different strategies were used: one with the molecules confined to the electrode surface and a second withDgAOR in solution....

10p dell39 03-04-2013 42 4   Download

The cytochromebc1 complex of the yeastSaccharomyces cerevisiae is composed of 10 different subunits that are assembledas a symmetrical dimer in the innermitochondrial membrane. Three of the subunits contain redox centers and participate in catalysis, whereas little is known about the function of the seven supernumerary subunits.

10p dell39 03-04-2013 65 4   Download

Mitochondria, which are the cellular energy plants, also act as the integra-tion center of cellular signaling pathways. Apoptosis is a well-known pathway in which mitochondria are involved. Protein kinase Cehas been classified as a novel type of protein kinase C and is involved in many cellular events regulating mitochondrial function.

9p galaxyss3 07-03-2013 32 3   Download

We have shown that hormone-induced downregulation of luteinizing hor-mone receptor (LHR) in the ovary is post-transcriptionally regulated by an mRNA binding protein. This protein, later identified as mevalonate kinase (MVK), binds to the coding region of LHR mRNA, suppresses its transla-tion, and the resulting ribonucleoprotein complex is targeted for degrada-tion.

11p galaxyss3 07-03-2013 33 5   Download

Native and Ca 2+ -depleted light-harvesting–reaction center core complexes (LH1–RC) from the photosynthetic bacterium Thermochromatium(Tch.) tepidum exhibit maximal LH1–Qy absorption at 915 and 889 nm, respec-tively. To understand the structural origins of the spectral variation, we performed spectroscopic and structure modeling investigations.

11p vinaphone15 27-02-2013 55 4   Download

Protein disulfide isomerase (PDI) and other PDI family proteins are mem-bers of the thioredoxin superfamily and are thought to play important roles in disulfide bond formation and isomerization in the endoplasmic reticulum (ER). The exact functions of PDI family proteins in plants remain unknown.

12p vinaphone15 25-02-2013 38 4   Download

A new set of experimental kinetic data on the hydrolysis of a series of phenylacetylp-substituted anilides catalyzed by penicillin G acylase from Escherichia coli(PGA) is presented in this article. The Hammett plot of log(kcat,R ⁄kcat,H) versus rp ) has three linear segments, which distinguishes the enzyme from the other N-terminal nucleophile hydrolases for which data are available.

10p viettel02 22-02-2013 46 4   Download

NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris Hikaru Hemmi1, Atsushi Kuno2, Shigeyasu Ito2,3, Ryuichiro Suzuki2,3, Tsunemi Hasegawa3 and Jun Hirabayashi2 1 National Food Research Institute, National Agriculture and Food Research Organization (NARO), Tsukuba, Japan 2 Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan 3 Department of Material and Biological Chemistry, Yamagata University, Yamagata, Japan Keywords earthworm Lumbricus ...

11p viettel02 22-02-2013 80 3   Download

Ở Nhật Bản đàn ông có tuổi thọ trung bình là 79 và phụ nữ là 85 (cao nhất thế giới trong 20 năm). Vậy lý do và yếu tố để người Nhật có tuổi thọ cao là gì? .Trong khi hợp tác với Giáo sư Alexander Leaf (Harvard Medical School, Boston, Mỹ), Giáo sư Yasuo Kagawa (trường Y khoa Jichi, Tochigi-Ken, Nhật Bản) đã lựa chọn vùng để khảo sát và tìm hiểu những điều khác biệt đáng kể về tuổi thọ. Trong báo cáo của ông gửi đến Trung tâm Anti-Aging Center-Châu Âu, ông cung cấp một bản phân...

4p rhea75 21-02-2013 88 2   Download