Meiosis

Spermatogenesis is a complex process involving mitotic cell division, meiosis, and spermiogenesis. This study aimed to examine the therapeutic effects and mechanisms of Panax ginseng in improving spermatogenesis, using a systematic network pharmacology approach and molecular docking.

14p viharuno 03-01-2025 8 2   Download

Bài giảng Chương 2: Bộ NST người và các kiểu đột biến NST trình bày về SS hữu tính và ổn định bộ NST; hình thái học NST eukaryote; tâm động và các kiểu NST; telomere; các kiểu băng NST; chu kỳ tế bào (cell cycle); giảm phân (meiosis); sự phát sinh giao tử;...Mời bạn đọc cùng tham khảo.

17p conchimnon32 26-06-2014 156 10   Download

The primary purpose of the present study was to investi-gate whether DNA replication at meiotic prophase also requires replication factors, especially proliferating cell nuclear antigen (PCNA). We cloned PCNA cDNAs (CoPCNA) from a cDNA library made from basidia of the basidiomycete,Coprinus cinereus. Interestingly, although CoPCNAis a single-copy gene in the genome, two di€er-entPCNAcDNA species were isolated using degenerate primers and a meiotic cDNA library, and were designated asCoPCNA-aandCoPCNA-b. ...

11p research12 29-04-2013 47 4   Download

Previously, the activity of DNA polymeraseawas found in the meiotic prophase I including non-S phase stages, in the basidiomycetes,Coprinus cinereus. To study DNA poly-merasea during meiosis, we cloned cDNAs for the C. cinereusDNApolymeraseacatalytic subunit (p140) and C. cinereusprimase small subunit (p48). Northern analysis indicated that both p140 and p48 are expressed not only at S phase but also during the leptotene/zygotene stages of meiotic prophase I.

10p fptmusic 16-04-2013 31 3   Download

Histones are modified post-translationally, e.g. by methylation of lysine and arginine residues, and by phosphorylation of serine residues. These modifications regulate processes such as gene expression, DNA repair, and mitosis and meiosis. Recently, evidence has been provided that histones are also modified by covalent binding of the vitamin biotin.

11p fptmusic 11-04-2013 40 2   Download

Rad51 and disrupted meiotic cDNA1 (Dmc1) are the two eukaryotic DNA recombinases that participate in homology search and strand exchange reactions during homologous recombination mediated DNA repair. Rad51 expresses in both mitotic and meiotic tissues whereas Dmc1 is confined to meiosis.

10p inspiron33 26-03-2013 55 5   Download

Sumoylation is a post-translational modification system that covalently attaches the small ubiquitin-related modifier (SUMO) to target proteins. Ubc9 is required as the E2-type enzyme for SUMO-1 conjugation to tar-gets. Here, we show that Ubc9 interacts with the meiosis-specific RecA homolog, Lim15⁄Dmc1 in the basidiomyceteCoprinus cinereus(CcLim15), and mediates sumoylation of CcLim15 during meiosis.

10p inspiron33 25-03-2013 39 5   Download

In this review, we describe the role of a small ubiquitin-like protein modi-fier (SUMO)-conjugating protein, Ubc9, in synaptonemal complex forma-tion during meiosis in a basidiomycete, Coprinus cinereus. Because its meiotic cell cycle is long and naturally synchronous, it is suitable for molecular biological, biochemical and genetic studies of meiotic prophase events.

13p galaxyss3 19-03-2013 28 2   Download

The Saccharomyces cerevisiae gene CSM1(SPO86, YCR086w) encodes a protein involved in sporulation - a process equivalent to gametogenesis in higher organisms. Sporulation is part of the yeast life cycle, tightly coupled to such processes as mitosis and meiosis, cell cycle control, genome stability, nutritional control, cell wall morphogenesis, or and intracellular transport.

26p galaxyss3 19-03-2013 42 5   Download

In eukaryotes, meiosis leads to genetically variable gametes through recom-bination between homologous chromosomes of maternal and paternal ori-gin. Chromatin organization following meiotic recombination is critical to ensure the correct segregation of homologous chromosomes into gametes. However, the mechanism of chromatin organization after meiotic recombi-nation is unknown.

10p media19 06-03-2013 44 2   Download

The DMC1 protein, a meiosis-specific DNA recombinase, promotes homol-ogous pairing and strand exchange. The I37N single nucleotide polymor-phism of the human DMC1 protein was reported as a result of human genome sequencing projects.

9p vinaphone15 27-02-2013 29 2   Download

This study investigated the potential of RNA interference, which is techni-cally challenging in bivalve mollusc species, to assess gene function in the oysterCrassostrea gigas. We designed dsRNA targeting the oyster vasa-like gene (Oyvlg), specifically expressed in oyster germ cells. In vivoinjection of oyvl-dsRNA into the gonad provokes a knockdown phenotype correspond-ing to germ cell underproliferation and prematurely arrested meiosis throu-gout the organ.

8p viettel02 22-02-2013 33 2   Download

Meiotic recombination is initiated by DNA double-stranded breaks intro-duced by the SPO11 protein. Despite a decade of research, the biochemical functions of SPO11 remain largely unknown, perhaps because of difficulties in studying the functionally active SPO11.

15p mobifone23 21-01-2013 48 4   Download

In meiosis, the accurate segregation of maternal and paternal chromosomes is accomplished by homologous recombination. A central player in meiotic recombination is the Dmc1 recombinase, a member of the RecA⁄Rad51 recombinase superfamily, which is widely conserved from viruses to humans.

9p mobifone23 18-01-2013 37 4   Download

One of the most obscure phenomena in modern biology is the near genome-wide displacement of histones that occurs during the postmeiotic phases of spermatogenesis in many species. Here we review the literature to show that, during spermatogenic differentiation, three major molecular mechanisms come together to ‘prepare’ the nucleosomes for facilitated disassembly and histone removal.

6p mobifone23 18-01-2013 44 4   Download

Sexual reproduction depends on the success of faithful chromosome trans-mission during meiosis to yield viable gametes. Central to meiosis is the process of recombination between paternal and maternal chromosomes, which boosts the genetic diversity of progeny and ensures normal homo-logous chromosome segregation.

19p mobifone23 18-01-2013 51 4   Download

Recombination of homologous chromosomes is essential for correct reduc-tional segregation of homologous chromosomes, which characterizes meio-sis. To accomplish homologous recombination, chromosomes must find their homologous partners and pair with them within the spatial con-straints of the nucleus.

6p mobifone23 18-01-2013 45 4   Download

The second minireview describes the importance of meiotic recombination in meiosis, and the current understanding of this process and its control mecha-nisms. Imperfections in meiotic recombination have been linked withde novo germline mutations, abnor-mal gametes, and infertility.

1p mobifone23 18-01-2013 55 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Apospory appears to accelerate onset of meiosis and sexual embryo sac formation in sorghum ovules

13p panasonic02 14-12-2011 35 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes

14p panasonic02 14-12-2011 54 5   Download