Obesity control

Inhibition of the mitochondrial adenine nucleotide translocator (ANT) by long-chain acyl-CoA esters has been proposed to contribute to cellular dys-function in obesity and type 2 diabetes by increasing formation of reactive oxygen species and adenosine via effects on the coenzyme Q redox state, mitochondrial membrane potential (Dw) and cytosolic ATP concentrations.

15p inspiron33 23-03-2013 56 4   Download

Sterol regulatory element-binding proteins 1 and 2 (SREBP-1 and SREBP-2) are important regulators of genes involved in cholesterol and fatty acid metabolism, but have also been implicated in the regulation of the cell cycle and have been associated with the pathogenesis of type 2 diabetes, atherosclerosis and obesity, among others.

13p viettel02 22-02-2013 37 3   Download

Obesity and its associated disorders, including diabetes and cardiovascular disease, have now reached epidemic proportions in the Western world, resulting in dramatic increases in healthcare costs. Understanding the pro-cesses and metabolic perturbations that contribute to the expansion of adi-pose depots accompanying obesity is central to the development of appropriate therapeutic strategies.

9p viettel02 20-02-2013 67 4   Download

Background: Dercum’s disease (DD) is characterised by obesity and chronic pain ( 3 months) in the adipose tissue. The pathogenesis of DD is unknown, but inflammatory components have been proposed. In previous reports and studies, an inconsistent picture of the histological appearance of the adipose tissue in DD has been described. The aim of this investigation was to examine the histological appearance of adipose tissue in patients with DD, with particular focus on inflammatory signs. Methods: Fat biopsies were sampled from painful regions from 53 patients with DD.

6p thulanh27 12-12-2011 70 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Histology of adipose tissue inflammation in Dercum’s disease, obesity and normal weight controls: a case control study...

6p thulanh26 09-12-2011 40 4   Download

Meeting report A burst of energy in metabolic disease research Jaswinder K Sethi Address: Department of Clinical Biochemistry, University of Cambridge, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 2QR, UK. E-mail: jks30@cam.ac.uk comment Published: 27 May 2004 Genome Biology 2004, 5:327 The electronic version of this article is the complete one and can be found online at http://genomebiology.

0p thulanh21 15-11-2011 53 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Dietary weight loss and exercise interventions effects on quality of life in overweight/obese postmenopausal women: a randomized controlled trial...

40p coxanh_8 05-11-2011 63 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Binge eating symptomatology in overweight and obese patients with schizophrenia: a case control study...

4p thulanh10 09-10-2011 62 4   Download