Pertussis toxin

Lysophosphatidicacid (LPA), oneof thenaturallyoccurring phospholipids, stimulates cellmotility through theactivation of Rho family members, but the signaling mechanisms remain tobe elucidated. In thepresent study,we investigated the roles of p21-activated kinase 1 (PAK1) onLPA-induced focal adhesion kinase (FAK) phosphorylation and cell motility.

9p dell39 03-04-2013 36 3   Download

Pertussis toxin, produced and secreted by the whooping cough agent Bordetella pertussis, is one of the most complex soluble bacterial proteins. It is actively secreted through the B. pertussiscell envelope by the Ptl secretion system, a member of the widespread type IV secretion systems.

15p cosis54 09-12-2012 65 3   Download