Phosphorothioateized

The inhibition of phosphatases by adenosine 5¢-phosphorothioate (AMPS) was first reported in the late 1960s; however, the structural basis for the inhibition has remained unknown. Here, it is shown that AMPS is a submi-cromolar inhibitor of class C acid phosphatases

8p cosis54 09-12-2012 44 2   Download