Transgene expres

Bioremediation presents a potentially low cost and environmentally agreeable alternative to current physico-chemical remediation strategies. However, heavy metals such as mercury cannot be converted into non-toxic forms by naturally occurring bacteria. Annual global emissions estimates for mercury released into the environment are in the thousands of tons per year [1,2] while the remediation cost is in the thousands of dollars per pound. Finding new bioremediation technologies is an urgent need.

8p zingzing09 24-04-2013 43 2   Download

A pair of nuclear receptors, ecdysone receptor (EcR) and ultraspiracle (USP), heterodimerize and transduce ecdysteroid signals. The EcR and its nonsteroidal ligands are being developed for regulation of transgene expres-sion in humans, animals and plants. In mammalian cells, EcR:USP heterodimers can function in the absence of ligand, but EcR⁄retinoid X receptor (EcR:RXR) heterodimers require the presence of ligand for activa-tion.

12p dell39 27-03-2013 42 4   Download

TheArabidopsis acd11mutant exhibits runaway, programmed cell death due to the loss of a putative sphingosine transfer protein (ACD11) with homology to mammalian GLTP. We demonstrate that transgenic expres-sion in Arabidopsis thalianaof human GLTP partially suppressed the phenotype of theacd11null mutant, resulting in delayed programmed cell death development and plant survival.

11p galaxyss3 07-03-2013 46 4   Download