Whey Products as Functional Foods

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In the early 1980’s, the Japanese were the first to recognize dairy components as having significant contributions to “physiologically functional foods.” Since then there has been an increasing number of investigations that have supported this view.Current evidence for the health benefits of most dairy foods and dairy components is based primarily on in vitro and in vivo animal studies. Human clinical studies are still needed in many areas.

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Nội dung Text: Whey Products as Functional Foods

WHEY PRODUCTS AS FUNCTIONAL FOODS FUNCTIONAL W. James Harper Department of Food Science & Technology The Ohio State University
Functional Foods Functional  Functional foods have been defined as “any food or food ingredient that may provide a health benefit beyond the traditional nutrients that it contains.”
Functional Dairy Foods Functional  In the early 1980’s, the Japanese were the first to recognize dairy components as having significant contributions to “physiologically functional foods.” Since then there has been an increasing number of investigations that have supported this view.
Functional Dairy Foods Functional  Current evidence for the health benefits of most dairy foods and dairy components is based primarily on in vitro and in vivo animal studies  Human clinical studies are still needed in many areas
Significant Functions Significant  Anti-microbial – including control of gut microflora  Anti-viral  Binding of E coli and cholera enterotoxins  Anti-cancer  Immunomodulation  Anti-oxidative  Opioid effects  Retard osteoporosis
Cardiovascular Functions Cardiovascular Anti-inflammatory Anti-hypertensive Anti-thrombic Cholesterol reduction
Whey Products and Whey Components with Bioactive Functions with
WHEY PRODUCTS WITH POTENTIAL HEALTH BENEFITS POTENTIAL  Whey Protein Concentrates – 34 to 85% protein  Whey Protein Isolates – Ion exchange and membrane processed  Whey Protein Fractions – Lactoferrin, Lactoperoxidase  Whey Protein Hydrolysates – Bioactive peptide concentrates  Whey Salts From Permeate – Enriched in calcium salts
Almost All Milk Components May Contribute Potential Health Benefits - Including Benefits  Proteins  Peptides  Lipids  Minor Carbohydrates  Minerals  Vitamins
AND AND Almost all bioactive milk Almost components are found in whey components
Whey Composition Whey Component Sweet whey Acid whey Total solids 6.5% 6.4% Protein 0.6%` 0.54% Lipids 0.25% 0.05% Lactose 5.0% 4.5% Ash 0.52% 0.6% Lactic acid 0.14% 0.47%
Sweet Whey Proteins Sweet 55% Beta lactoglobulin Alpha lactalbumin 15% Immunoglobulins 15% BSA 5% Lactoferrin
Whey Lipids Whey  About 50% of whey lipids are phospholipids derived from small fat globules and fat globule membrane  Bioactive lipids in whey include: – Conjugated Linoleic Acid (CLA) – Sphingolipids – Ether lipids – Butyric acid
Relationship between Bioactive Function and Whey Components and
ANTI-CANCER POTENTIAL ANTI-CANCER
Anti-cancer activity reported for the following cancers* the  Colon (c)  Prostate (p)  Gastric/stomach (g)  Breast (b)  Skin (s) *based on cellular and animal models
Protection from Some Cancers Protection WPC LF/LP CLA BSA Peptides Cancer colon + + + + + breast + + + + skin + prostate (+) + + gastric +
Other possible protectants include include  Colon Cancer – Sphingolipids – Butyric acid – Calcium – GMP  Breast Cancer – Alpha-lactalbumin – MFGM protein
CARDIOVASCULAR EFFECTS EFFECTS
Components with Cardiovascular Effect Cardiovascular Activity WPC WPI Peptides LF B-vit. Other Hypertension + + + (Ca) + Anti- +* + inflammatory Anti-thrombic + + + Reduce Stearic + + cholesterol acid