Anti-bacterial activity

Camellia megasepala Hung T. Chang & Trin Ninh, found in Na Hang district, Tuyen Quang province, contains a significant amount of flavonoids and polyphenols, which are important phenolic compounds known for their various biological activities beneficial to human health, including antibacterial and antiinflammatory effects. This study applied the response surface methodology (RSM) to examine the influence of extraction factors on the polyphenol and flavonoid content in golden tea leaves.

8p vijiraiya 19-05-2025 1 1   Download

Natural polysaccharides from algae have gained increasing attention for their biological activities and potential for applications in food, pharmacology, medicine, and biology fields. The study aimed to investigate the effects of the Viscozyme enzyme on the polysaccharide extraction from Sargassum oligocystum algae.

8p visarada 28-04-2025 1 1   Download

This study contributes to the scientific data on binary combinations by investigating the synergistic antibacterial activity of the binary combination of MM or MQ EOs with thymol. This research is significant as it contributes to the global effort to combat antimicrobial resistance, providing a potential solution to this pressing public health challenge.

13p viling 11-10-2024 5 1   Download

Spirulina platensis biopigments have been potential source of nutritional, pharmacological and cosmetical purposes due to the presence of bioactive pigments. In this study, Spirulina platensis was culture in the labotory to extract using a glucose/glycerol and water-based NADES.

8p viaburame 14-03-2025 2 1   Download

FtsZ is conserved in almost all bacteria and is an essential protein for bacterial cell division. The cell division is prevented by the inhibitors against FtsZ’s functions. Thus, FtsZ is known as an attractive, and underexploited novel antibacterial target protein. The aim of this research is searching for new antibacterial agents from 72 plants collected in Central Vietnam.

6p viuchiha 03-01-2025 3 2   Download

A new series of transition metal complexes of Co(III), Ni(II) and VO(IV) was synthesized with the bidentate Schiff base ligand (HL) derived from the condensation of 2-amino-3-benzyloxypyridine and 5-bromo salicylaldehyde.

14p tocectocec 25-05-2020 31 2   Download

A group of new fluoroaniline Schiff bases (3a–3f) were synthesized and structurally characterized by various spectroscopic techniques such as 1H-NMR, LC-MS and FT-IR spectral studies.

8p tocectocec 25-05-2020 19 1   Download

A series of novel 5-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine linked various sulfonamide derivatives 8a-8j poly functionalized were designed and synthesized in moderate to good yield.

10p tocectocec 25-05-2020 16 1   Download

Ethanolic and aqueous (hot and cold) extracts of the fruit pulp, stem bark and leaves of Tamarindus indica were evaluated for antibacterial activity, in vitro, against 13 Gram negative and 5 Gram positive bacterial strains using agar well diffusion and macro broth dilution techniques, simultaneously.

12p tanbnhp 22-03-2014 50 6   Download

Members of the proline-rich antibacterial peptide family, pyrrhocoricin, apidaecin and drosocin appear to kill responsive bacterial species by binding to themultihelical lid region of the bacterial DnaK protein.Pyrrhocoricin, the most potent among these peptides, is nontoxic to healthy mice, andcanprotect these animals frombacterial challenge.

12p research12 23-04-2013 36 3   Download

Microcin J25 (MccJ25) is the single macrocyclic antimicro-bial peptidebelonging to the ribosomally synthesizedclass of microcins that are secreted byEnterobacteriaceae.Itshowed potent antibacterial activity against severalSalmonellaand Escherichiastrains and exhibited a compact three-dimen-sional structure [Blondet al. (2001) Eur. J. Biochem., 268, 2124–2133]. The molecular mechanisms involved in the biosynthesis, folding andmode of action of MccJ25 are still unknown.

11p tumor12 22-04-2013 44 2   Download

Peptides composed of leucyl and lysyl residues (
LK pep-tides) with different compositions and sequences were compared for their antibacterial activities usingcell wall-less bacteria of the classMollicutes(acholeplasmas, mycoplas-mas and spiroplasmas) as targets. The antibacterial activity of the amphipathica-helical peptides varied with their size, 15 residues beingthe optimal length, independent of the membrane hydrophobic core thickness and the amount of cholesterol.

11p fptmusic 16-04-2013 40 3   Download

Cationic antimicrobial peptides are naturally occurring antibiotics that are actively being explored as a new class of anti-infective agents. We recently identified three cathelicidin antimicrobial peptides from chicken, which have potent and broad-spectrum antibacterial activitiesin vitro (Xiao Y, Cai Y, Bommineni YR, Fernando SC, Prakash O, Gilliland SE & Zhang G (2006)J Biol Chem281, 2858–2867).

13p inspiron33 26-03-2013 52 4   Download

Antimicrobial peptides are effector molecules of the innate immune system. We have recently shown that peptides containing multiples of the heparin-binding Cardin and Weintraub motifs AKKARA and ARKKAAKA exert antimicrobial activities. Here, we show that replacement of lysine and arginine in these motifs by histidine abrogates the antibacterial effects of these peptides.

8p inspiron33 26-03-2013 50 4   Download

Cathelicidins are an important family of cationic host defense peptides in vertebrates with both antimicrobial and immunomodulatory activities. Fowlicidin-1 and fowlicidin-2 are two newly identified chicken cathelicidins with potent antibacterial activities. Here we report structural and func-tional characterization of the putatively mature form of the third chicken cathelicidin, fowlicidin-3, for exploration of its therapeutic potential.

11p inspiron33 23-03-2013 42 3   Download

Histidine-rich glycoprotein (HRGP), an abundant heparin-binding protein found in plasma and thrombocytes, exerts antibacterial effects against Gram-positive bacteria (Enterococcus faecalisand Staphylococcus aureus) and Gram-negative bacteria (Escherichia coliandPseudomonas aeruginosa). Fluorescence studies and electron microscopy to assess membrane permea-tion showed that HRGP induces lysis of E.

13p inspiron33 23-03-2013 51 5   Download

Fish skin mucus contains a variety of antimicrobial proteins and peptides that seem to play a role in self defense. We previously reported an antibac-terial protein in the skin secretion of the rockfish, Sebastes schlegeli, which showed selective antibacterial activity against Gram-negative bacteria. This study aimed to isolate and structurally and functionally characterize this protein.

12p inspiron33 23-03-2013 54 4   Download

Eppin has two potential protease inhibitory domains: a whey acid protein or four disulfide core domain and a Kunitz domain. The protein is also reported to have antibacterial activity against Gram-negative bacteria. Eppin and its whey acid protein and Kunitz domains were expressed in Escherichia coliand their ability to inhibit proteases and kill bacteria compared.

9p media19 06-03-2013 30 2   Download

The crystal structure of uridine monophosphate kinase (UMP kinase, UMPK) from the opportunistic pathogenUreaplasma parvumwas deter-mined and showed similar three-dimensional fold as other bacterial and archaeal UMPKs that all belong to the amino acid kinase family.

12p media19 05-03-2013 39 3   Download

Daptomycin and A21987C antibiotics are branched, cyclic, nonribosomally assembled acidic lipodepsipeptides produced byStreptomyces roseosporus. The antibacterial activity of daptomycin against Gram-positive bacteria strongly depends on the nature of the N-terminal fatty acid moiety.

7p vinaphone15 28-02-2013 28 3   Download