Cytotoxicity

To establish a protocol for analyzing NK cell cytotoxic activity (NKAc) in breast cancer patients using the flow cytometric technique. Methods: We first optimized the protocol based on the previously published studies, focusing on choosing fluorescent dye concentration, incubation time length, and Effector:Target cell ratio (E:T ratio). Subsequently, we preliminarily applied the established protocol to characterize NKAc in some breast cancer patients and healthy controls.

9p vimitsuki 06-05-2025 3 1   Download

A benzothiazole ring plays an important role in pharmacological target diseases, including metabolic diseases, cancer, anti-inflammatory, neurodegeneration, viral diseases, bacterial infections, fibrosis, and thrombosis. Hydrazone-hydrazide derivatives are present in numerous biological molecules and play a significant role in medicine and pharmacology.

9p viaburame 14-03-2025 2 1   Download

Luận án Tiến sĩ Hóa học "Nghiên cứu thành phần hóa học và hoạt tính chống ung thư của hai loài Xương quạt (Dianella ensifolia) và Côm hải nam (Elaeocarpus hainanensis)" trình bày các nội dung chính sau: Phân lập các hợp chất từ loài Xương quạt (Dianella ensifolia) và Côm hải nam (Elaeocarpus hainanensis) bằng các phương pháp sắc ký; Đánh giá hoạt tính gây độc tế bào ung thư (cytotoxicity) của các chất sạch phân lập được. Chất có hoạt tính tốt được nghiên cứu tác động chống ung thư ở mức độ phân tử.

292p vilazada 02-02-2024 18 4   Download

The objectives of the thesis: Isolation and determination of chemical structures of the isolated compounds from the leaves of Excoecaria agallocha L. and Excoecaria cochinchinensis Lour.; studied the cytotoxic, anti-inflammatory, and antimicrobial activities of the isolated compounds to find the bioactive compounds.

27p closefriend09 16-11-2021 34 3   Download

The objectives of the thesis: Determine the chemical composition of three soft coral species S. nanolobata, S. conferta, S. leptoclados collected in the central sea of Vietnam; đetecting active substances with cytotoxic activity in soft corals studied, orienting their application for biomedical and pharmacological studies.

26p closefriend09 16-11-2021 17 4   Download

Demonstrating the main chemical constituents of Anodendron paniculatum (Roxb.) A.DC. Structural determination of isolated compounds; evaluation of the cytotoxic activities of isolated compounds against human cancer cell lines.

25p nguathienthan12 23-05-2021 14 3   Download

The aim of the thesis: Study on chemical constituents of two Knema species including Knema pachycarpa and Knema saxatilis growing in Vietnam. Evaluate cytotoxic and cetylcholinesterase enzyme inhibitory activitiesof isolates to find out bioactive compounds.

25p extraenglish 24-05-2021 21 4   Download

The aim of the thesis: Study on chemical constituents of two Tacca species including Tacca vietnamensis and Tacca chantrierri growing in Vietnam; evaluate cytotoxic and inflammatory activities of isolates to find out bioactive compounds.

27p capheviahe27 23-02-2021 31 4   Download

The objectives of the thesis: Study on chemical constituents of three Trichosanthes species (T. baviensis, T. anguina, and T. kirilowii) grown in Vietnam; evaluation of cytotoxic and tyrosinase enzyme inhibitory activities of isolated compounds from the above mentioned Trichosanthes species.

14p capheviahe26 25-01-2021 20 3   Download

Study on chemical constituents of two Knema species including Knema pachycarpa and Knema saxatilis growing in Vietnam; evaluate cytotoxic and cetylcholinesterase enzyme inhibitory activitiesof isolates to find out bioactive compounds.

25p capheviahe26 25-01-2021 22 4   Download

Summary of Chemistry doctoral thesis: Study on isolation and investigation of antibiotic and cytotoxic activity of secondary compounds from three actynomycetes strains Streptomyces G246, G261, G248 collected in some central East Vietnam sea

26p larachdumlanat129 20-01-2021 42 5   Download

Obtaining of secondary metabolites from marine fungi isolated in the Central Vietnam and identifying some biological activities (antibiotimicrobial, cytotoxic, antioxidant, neuroprotective activities) of obtained individual compounds.

27p trinhthamhodang7 31-08-2020 44 2   Download

New ruthenium(III) complexes with 3-(Benzothiazol-2-yliminomethyl)-phenol (HL) ligand have been synthesized and characterized with the aid of elemental analysis, IR, electronic, and electron paramagnetic resonance spectroscopic techniques.

12p tocectocec 25-05-2020 12 3   Download

The selectivity index of these compounds is similar to that of cidofovir. Although antiviral activity was evident in secondary assays, significant virus inhibition occurred at or near the cytotoxic concentration (SI90=1).

8p tocectocec 25-05-2020 13 1   Download

A series of fourteen chalcone was synthesized via. Claisen–Schmidt condensation between substituted 2- hydroxyl acetonaphthones and substituted benzaldehyde in presence of tripotassium phosphate (K3PO4) catalyst.

16p tocectocec 25-05-2020 10 1   Download

Objectives of the thesis: Research to clarify the main chemical composition of two species of G. glomerulatum, G. hirsutum in Vietnam. Evaluation of toxic activity cells of isolated compounds to search for bioactive compounds, as a scientific basis for further research to create care products health for the community and contribute to explaining the curative effect of these species.

27p xacxuoc4321 09-07-2019 54 5   Download

The thesis aims to study the chemical composition and survey the biological activity of two species: the lizard (B. laxiflora) and the cow breast (F. hirta). - Isolate and determine the chemical structure of two species of whole lizard (B. laxiflora) and the root of cow breast (F. hirta). Evaluation of some cytotoxic activity, anti-inflammatory activity, anti-proliferation activity on acute bone marrow cell line (OCI-AML) of extracting extracts and of some isolated compounds to orient for Next application studies.

27p xacxuoc4321 11-07-2019 55 4   Download

The objective of the thesis is to study to clarify the main chemical composition of two species C.novaeguinea and P. gracilis in the Northeast sea of ​​Vietnam. Evaluate the cytotoxic activity of some isolated compounds to search for bioactive compounds.

28p xacxuoc4321 11-07-2019 28 4   Download

The research objectives of the dissertation isolate and determine the structure of clean compounds from mondo grass root roots. Evaluate cytotoxic effects and anti-inflammatory activity based on the effect of inhibiting NO production of isolated compounds.

27p xacxuoc4321 11-07-2019 45 3   Download

The objective of the thesis is to build the synthesis process of Analogs of Bengamide A and E, conduct the biological activity of the synthesized Analogs. To find out more about the details of the content, please consult the thesis summary.

27p xacxuoc4321 11-07-2019 31 3   Download