Lung cancer

To evаluаte 18FDG PET-CT for the prediction of overаll survivаl in pаtients with smаll cell lung cаncer аfter concurrent chemoradiotherapy. Methods: Forty pаtients with pаthologicаlly proven stаge III аnd III SCLC hаd FDG PET-CT scаns before concurrent chemorаdiotherаpy. The mаximum stаndаrdized uptаke vаlue (SUVmаx) of the primаry lung lesion wаs cаlculаted.

6p vihizuzen 26-05-2025 2 1   Download

To evaluate the diagnostic value of PTGER4 (Prostaglandin E Receptor 4) gene methylation in plasma for lung cancer detection compared to healthy controls. Methods: A cross-sectional, case-control study was conducted on 149 non-small cell lung cancer (NSCLC) patients and 100 healthy individuals. Peripheral blood samples were collected for PTGER4 methylation analysis using real-time methylation-specific PCR (MSP).

8p vimitsuki 06-05-2025 1 1   Download

The images of diffuse lung involvement are seen in various respiratory diseases, including lung adenocarcinoma (ADC). After ruling out acute infectious causes, lung biopsy is valuable for a definitive diagnosis, with transbronchial biopsy via flexible bronchoscopy being an effective and safe diagnostic approach.

8p vimitsuki 06-05-2025 3 1   Download

To evaluate the prevalence of sarcopenia and its associated factors in lung cancer patients undergoing chemotherapy at a tertiary hospital in Vietnam. Methods: A cross-sectional descriptive study was conducted on 89 lung cancer patients. Sarcopenia was assessed using the Asian Working Group for Sarcopenia (AWGS) 2019 criteria, including measurements of handgrip strength (HGS), appendicular skeletal muscle mass (ASM), and physical performance.

9p vimitsuki 06-05-2025 1 1   Download

This study aims to present a case of pneumonitis in a patient treated with concurrent chemoradiotherapy (cCRT) followed by durvalumab, focusing on the clinical manifestations, management strategies, and the implications for medical practice.

6p viyamanaka 06-02-2025 6 2   Download

UNG THƯ PHỔI.Ths. VÕ PHẠM MINH THƯ...Định nghĩa.Là sự tăng trưởng không kiểm soát của các tế bào ác tính ở một hay hai phổi và cây khí phế quản.  Là hậu quả của sự tiếp xúc lâu dài với

40p sony_12 26-06-2013 44 3   Download

Bài giảng Ung thư phổi lung cancer trình bày nguyên nhân gây ung thư phổi, cách phát hiện ung thư phổi, tổn thương giải phẫu bệnh, di căn ung thư phổi. Đây là tài liệu học tập và tham khảo dành cho sinh viên ngành Y.

35p qlngoc 22-05-2014 125 33   Download

The research objectives of the thesis: Isolate and determine the chemical structure of compounds from C. candicans and C. macrophylla species collected in Vietnam. Assessment of toxic activity on some cancer cell lines: liver (Hep-G2), lung (Lu-1) and breast (MCF-7) of isolated clean compounds. Researching the chemical composition of C. candicans and C. macrophylla essential oils

29p extraenglish 24-05-2021 21 4   Download

Isolate and determine the chemical structure of compounds from C. candicans and C. macrophylla species collected in Vietnam; assessment of toxic activity on some cancer cell lines: liver (Hep-G2), lung (Lu-1) and breast (MCF-7) of isolated clean compounds, researching the chemical composition of C. candicans and C. macrophylla essential oils.

29p capheviahe26 25-01-2021 38 3   Download

Assessed the level of mRNA expression of CIZ1b, VEGF, EGFR mutations and the rate of Merkel cell infection in patients with non-small cell lung cancer. Assessed the level of mRNA expression of CIZ1b, VEGF, EGFR mutations and the rate of Merkel cell infection in patients with non-small cell lung cancer.

32p trinhthamhodang7 31-08-2020 38 3   Download

Research the results of the application of follow-up and diagnosis of nodules in the lungs of Mayo Clinic hospital-United States after 3-6 months.

31p angicungduoc6 21-07-2020 38 3   Download

To describe the clinical and subclinical features of lung cancer patients with EGFR mutations before TKIs therapy and in the relapsed period. To identify the T790M mutation and MET amplification in patients with lung cancer and EGFR-TKIs resistance and the relationship with clinical and subclinical features.

29p cothumenhmong6 17-07-2020 14 2   Download

Regulators of G protein signaling (RGS) proteins modulate G protein-coupled receptor (GPCR) signaling networks by terminating signals produced by active Gα subunits. RGS17, a member of the RZ subfamily of RGS proteins, is typically only expressed in appreciable amounts in the human central nervous system, but previous works have shown that RGS17 expression is selectively upregulated in a number of malignancies, including lung, breast, prostate, and hepatocellular carcinoma.

10p caothientrangnguyen 09-05-2020 14 1   Download

We report the biochemical characterization of calhepatin, a calcium-binding protein of the S100 family, isolated from lungfish (Lepidosiren paradoxa) liver. The primary structure, determined by Edman degradation and MS/MS, shows that the sequence identities with the other members of the family are lower than those between S100 proteins from different species. Calhepatin is composed of 75 residues and has a molecular mass of 8670 Da. It is smaller than calbindin D9k (78 residues), the smallest S100 described so far....

9p research12 01-06-2013 48 4   Download

Several clinical trialshave revealed that individualswhowere givenb)carotene and vitamin Adid not have a reduced risk of cancer compared to those given placebo 2,3 ; 2,3 rather, vita-min A could actually have caused an adverse effect in the lungs of smokers [Omenn, G.S., Goodman, G.E., Thorn-quist, M.D., Balmes, J., Cullen, M.R., Glass, A., Keogh, J.P., Meyskens, F.L., Valanis, B., Williams, J.H., Barnhart, S. & Hammar, S.N. Engl. J. Med(1996) 334, 1150–1155; Hennekens, C.H., Buring, J.E.,Manson, J.E., Stampfer,M., Rosner,B.,Cook,N.R.,Belanger,C.,LaMotte,F.,Gazi-ano, J.M., Ridker, P.M.

9p tumor12 20-04-2013 38 2   Download

Exposure to quartz particles induces a pathological process named silicosis. Alveolar macrophages initiate the disease through their activation, which is the origin of the later dysfunctions. Ascorbic acid is known to selectively dissolve the quartz surface. During the reaction, ascorbic acid progressively disappears and hydroxyl radicals are generated from the quartz surface. These observations may be relevant to mammalian quartz toxicity, as sub-stantial amounts of ascorbic acid are present in the lung epithelium. ...

14p inspiron33 23-03-2013 42 4   Download

The multidrug resistance-associated protein transporter ABCC1 (MRP1) is an integral plasma membrane protein involved in the multidrug resistance phenotype. It actively expels a number of cytotoxic molecules from cells. To gain insight into the modulation of the functional properties of this integral membrane protein by cholesterol, a main component of the lipid bilayer, we used multidrug-resistant GLC4⁄ADR cells,

11p galaxyss3 21-03-2013 48 5   Download

Integrin b4 is a tissue-specific protein, but its role in autophagy of lung adenocarcinoma cells is not clear. In this study, we used microtubule-associated protein 1 light chain 3 processing and acridine orange staining to reveal that knockdown of integrin b4 by its specific siRNA induced autophagic cell death in A549 lung cancer cells.

8p vinaphone15 28-02-2013 26 2   Download

The transcription factor ZBP-89 has been implicated in the induction of growth arrest and apoptosis. In this article, we demonstrate that ZBP-89 was able to restrain senescence in NCI-H460 human lung cancer cells, through epigenetically regulating p16 INK4a expression.

10p vinaphone15 25-02-2013 36 2   Download

a-defensins are released from granules of leukocytes and are implicated in inflammatory and fibrotic lung diseases. In the present study, the effects of a-defensins on the proliferation and collagen synthesis of lung fibroblasts were examined. We found thata-defensin-1 and a-defensin-2 induced dose-dependent increases in the incorporation of 5-bromo-2¢-deoxy-uridine into newly synthesized DNA in two lines of human lung fibroblasts (HFL-1 and LL-86)

12p viettel02 20-02-2013 41 4   Download