
Báo cáo khoa học: Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans
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Candida albicansis the most prevalent yeast pathogen in humans, and recently it has become increasingly resistant to the current antifungal agents. In this study we investigatedC. albicansdihydroorotate dehydroge-nase (DHODH, EC 1.3.99.11), which catalyzes the fourth step ofde novo pyrimidine synthesis, as a new target for controlling infection.
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