
Báo cáo khoa học: Biosynthesis of isoprenoids – studies on the mechanism of 2C-methyl-D-erythritol-4-phosphate synthase
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2C-Methyl-d-erythritol-4-phosphate synthase, encoded by the ispC gene (also designated dxr), catalyzes the first committed step in the nonmevalo-nate isoprenoid biosynthetic pathway. The reaction involves the isomeriza-tion of 1-deoxy-d-xylulose 5-phosphate, giving a branched-chain aldose derivative that is subsequently reduced to 2C-methyl-d-erythritol 4-phos-phate.
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