
Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver
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The molecular adaptor Grb14 bindsin vitro to the activated insulin receptor (IR) and inhibits IR signaling. In this study, we have used rat liver subcel-lular fractionation to analyze in vivo insulin effects on Grb14 compartmen-talization and IR phosphorylation and activity.
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