
Báo cáo khoa học: Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl
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Cbl is an adaptor protein and ubiquitin ligase that binds and is phosphory-lated by the nonreceptor tyrosine kinase Src. We previously showed that the primary interaction between Src and Cbl is mediated by the Src homology domain 3 (SH3) of Src binding to proline-rich sequences of Cbl.
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