
Báo cáo khoa học: Leukocyte adhesion deficiency II Advances and open questions
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Leukocyte adhesion deficiency II (LAD II) belongs to a group of human congenital diseases in which the interactions of leukocytes with the vascular endothelium are strongly impaired. LAD II is based on a defect in the syn-thesis of fucosylated glycostructures. This leads to an immunodeficiency owing to the absence of functional selectin ligands and to strong psycho-motor defects, as a result of as-yet unknown reasons.
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