Báo cáo khoa học: Non-hydrolytic functions of acetylcholinesterase The significance of C-terminal peptides

This review explores the possibility that acetylcholinesterase may play a pivotal, non-hydrolytic role in neurodegeneration. More specifically, C-ter-minal sequences of acetylcholinesterase may act as signalling molecules in key brain regions characteristically vulnerable to Alzheimer’s, Parkinson’s and motor neuron disease.