intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

43
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Uniquely amongst vitamin K-dependent coagulation proteins, protein C interacts via its Gla domain both with a receptor, the endothelial cell protein C receptor (EPCR), and with phospholipids. We have studied naturally occurring and recombinant protein C Gla domain variants for soluble (s)EPCR binding, cell surface activation to activated protein C (APC) by the thrombin–thrombomodulin complex, and phospholipid dependent factor Va (FVa) inactivation by APC, to establish if these functions are concordant. ...

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2