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Báo cáo khoa học: The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:18

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Isocitrate dehydrogenase (IDH) from the hyperthermophile Thermotoga maritima(TmIDH) catalyses NADP + - and metal-dependent oxidative decarboxylation of isocitrate toa-ketoglutarate. It belongs to the b-decarb-oxylating dehydrogenase family and is the only hyperthermostable IDH identified within subfamily II. Furthermore, it is the only IDH that has been characterized as both dimeric and tetrameric in solution.

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Nội dung Text: Báo cáo khoa học: The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima

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