intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

38
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Cyclooxygenase-2 (COX-2) is a key enzyme in the production of prosta-glandins that are major inflammatory agents. COX-2 production is trig-gered by exposure to various cytokines and to bacterial endotoxins. We present here a novel role for the Ets transcription factor ESE-1 in regula-ting the COX-2gene in response to endotoxin and other pro-inflammatory stimuli. We report that the induction of COX-2expression by lipopoly-saccharide (LPS) and pro-inflammatory cytokines correlates with ESE-1 induction in monocyte⁄macrophages. ...

Chủ đề:
Lưu

Nội dung Text: Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2