
Báo cáo Y học: Regulated expression and intracellular localization of cystatin F in human U937 cells
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Cystatin F is a cysteine peptidase inhibitor recently discov-ered in haematopoietic cells by cDNA cloning. To further investigate the expression,distribution and properties of the native human inhibitor the promyeloid cell line U937 has beenstudied.The cells expressedrelatively largequantities of cystatin F,which was found both secreted and intracellu-larly. The intracellular levels were unusually high for a secreted cystatin (25% of the cystatin F in 2- or 4-day culture medium).
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