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Báo cáo Y học: Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:7

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The present study was conducted on human Jurkat T-cell lines in order to elucidate the role of phospholipase A2in capacitative calcium entry. We have employed thapsigar-gin (TG)that induces increases in [Ca 2+ ] i by emptying the calcium pool of endoplasmic reticulum, followed by capacitative calcium entry. We designed a Ca 2+ free/Ca 2+ reintroduction (CFCR)protocol for the experiments, conducted in Ca 2+ -free medium.

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Nội dung Text: Báo cáo Y học: Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells

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